SYMPTOMATIC MANAGEMENT OF MULTIPLE SCLEROSIS

Abstract

Multiple sclerosis is a chronic, inflammatory, demyelinating disease associated with a wide variety of different symptoms. The disease-modifying medications are only partially effective and do not ameliorate irreversible axonal injury, which produces the main symptoms of multiple sclerosis. Successful symptom management is a key determinant of quality of life for the patients with multiple sclerosis. The present article summarizes the main therapeutic options available for fatigue, spasticity, pain, tremor and ataxia, gait disorders, psychiatric disorders and cognitive impairment, oculomotor disorders, brainstem symptoms, neurogenic bladder disorder, neurogenic bowel dysfunction and sexual dysfunction.