ANTI-MUSK POSITIVE OCULAR MYASTHENIA – A CASE REPORT AND REVIEW OF LITERATURE

Abstract

In this article we report a case of ocular myasthenia that was positive for anti-muscle-specific tyrosine kinase (MuSK) antibodies. The patient is a 28 year old woman who exhibited intermittent diplopia and slight bilateral lid ptosis without any generalised symptoms since at least three years. She showed significant improvement after receiving treatment with prednisolone. Ocular MG with anti-MuSK antibodies lasting for a long term has rarely been described. Our conclusion is that ocular MG is a rare presentation of the anti-Musk antibody syndrome and should be investigated in patients presenting with external opthalmoplegia and a negative result for anti-acetylcholine receptor (AChR) antibodies.