CEREBRAL AMYLOID ANGIOPATHY: CASE REPORT AND LITERATURE REVIEW

Authors

  • I. Nikolaidis
  • K. Natsis
  • P. Maiovis
  • D. Parisis
  • D. Karakostas
  • P. Ioannidis

Keywords:

Cerebral amyloid angiopathy, amyloid-b protein, cerebrovascular disorders, MRI

Abstract

The cerebral amyloid angiopathy (CAA) is a common disease of small blood vessels, characterized by amyloid deposition in these, and separated into several types depending on the amyloid protein deposited. The angiopathy induced results in the manifestation of intracerebral hemorrhage, ischemic infarct, dementia, and encephalopathy. Of particular interest is the inflammatory form of the disease, as patients show a positive response to immunosuppressive therapy. Definitive diagnosis requires brain biopsy, but the development of valid diagnostic criteria and modern imaging methods allow the diagnosis clinically in some patients without brain biopsy. 
We describe an incident with possible inflammatory cerebral amyloid angiopathy. The purpose of the presentation is to highlight a recently recognized form of amyloid angiopathy requiring therapeutic treatment with immunosuppressive therapy.

Published

2017-12-01