MIGRAINE AND CALCITONIN PEPTIDE FAMILY: WHAT DO WE OVERLOOK BY FOCUSING ONLY ON CGRP AND HIS RECEPTOR?

Authors

Emmanouil V. Dermitzakis

Keywords:

migraine, CGRP, amylin, Calcitonin peptide family, adrenomedullin

Abstract

The newly released migraine medications target the Calcitonin-Gene Related Peptide (CGRP) or tis receptor.
The response of migraineurs to these new treatments is about 60%. This article mentions other
neuropeptides of the same Calcitonin peptide family and their receptors, whose role in the mechanism of
migraine should not be overlooked by focusing only on CGRP.