APPROACHING THE PATIENT WITH HEREDITARY NEUROPATHY

Authors

M. Breza
G. Koutsis
G. Karadima
M. Panas

Keywords:

inherited neuropathies, Charcot-Marie-Tooth disease, CMT, hereditary motor and sensory neuropathies, HMSN, HMN, HSAN, CMT1A, CMTX, HNPP

Abstract

Inherited neuropathies are a clinically and genetically heterogeneous group of diseases, which, taken together, are the commonest inherited neuromuscular disorder. The objective of the present review is to assist the clinical neurologist in approaching a patient with inherited neuropathy, focusing on the identification and differential diagnosis of these disorders. Α diagnostic algorithm is proposed and the most common types of inherited polyneuropathies are discussed. Finally, the treatment of inherited neuropathies is discussed and some recent, clinically significant advances in the field are briefly outlined.